X Wen,D Li, Y Zhang, S Liu, L Ghali, RK Iles (2012). Arsenic trioxide induces cervical cancer apoptosis but specifically targets Human Papillomavirus infected cell populations. Anti-Cancer Drugs. 23: 280–287
B Burczynska, SA Butler, X Wen, A Shiled, RK Iles (2011). Analysis of free beta subunit of hCG secretion by common epithelial cancer cell lines.39th Congress of the International Society of Oncology and Biomarkers, October 2011, Florence, Italy.
X Wen, D Li, AJ Tozer, SM Docherty, RK Iles(2010). Estradiol, progesterone, testosterone profiles in human follicular fluid and cultured granulosa cells from luteinized pre-ovulatory follicles. Reproductive Biology and Endocrinology, 8:117.
Xuesong Wen, Dong Li, Lucy Ghali, and Ray K Iles. (2010) Ectopic HCG beta may induce epithelialmensenchymal transition on human kera tinocytes in vitro and this could promote tumour progression and invasion. Tumour Biology, 31 (S44). ISSN 1010-4283
X. Wen, D Perrett, SM Docherty, AJ Tozer, RK Iles (2009). High follicular fluid adenosine levels may be pivotal in the metabolism and recycling of adenosine nucleotides in the human follicle.Metabolism. 59:1145-1155.
X. Wen, D Perrett, P. Patel, NJ Li, SM Docherty, AJ Tozer, RK Iles (2009). Capillary electrophoresis of human follicular fluid. J of Chromatography B. 877: 3946-52
D Li, X Wen, L Ghali , FM Al-Shalabi, SM Docherty, Patricia Purkis, Ray K Iles (2008).hCGbexpression by cervical squamous carcinoma - in vivo histological association with tumor invasion and apoptosis. Histopathology53: 147-155.
X Wen, AJ Tozer, D Li, SM Docherty, T Al-Sharwaf and RK Iles (2008). Human granulosa-lutein cell in vitro production of progesterone, inhibin-A, inhibin-B and activin-A are dependent on follicular size and not the presence of the oocyte. Fertility Sterility89:1406-13.
X Wen, L Ghali, D Li, N Li, R Iles. Ectopic hCG beta may induce Epithelial-Mensenchymal Transition on Human Keratinocytes in vitro and this could promote tumour progression and invasion. 38th Congress of the International Society of Oncology and Biomarkers, September 3rd-8th, 2010, Munich, Germany. Invited oral presentation.
X Wen, D Li, L Ghali, A Shiled, RK Iles. Human Chorionic Gonadotrophin beta expression and growth effects on Breast and Prostate cancer cell lines. 2nd International Conference on Gonadotrophin & Receptors, July 6-9th, 2008, Herdfordshire, UK.
A Shiled, X Wen, M Naase, F Hills, S. Butler, RK Iles. Fetal Calf Serum effects on the secretion of Human Chorionic Gonadotrophin beta by bladder cancer cell lines in vitro. 2nd International Conference on Gonadotrophin & Receptors, July 6-9th, 2008, Herdfordshire, UK.
X Wen, AJ Tozer, SA Butler, CM Bell, SM Docherty and RK Iles (2006). Follicular Fluid levels of Inhibin A, inhibin B and activin A levels reflect changes in follicle size but are not independent markers of oocyte ability to fertilize. Fertility Sterility 2006, 8(56): 1723-9.
D Li,XS Wen, SM Docherty, L Ghali, RK Iles. The beta subunit of hCG may have a role in anti-apoptosis, and in tumour invasion of cervical squamous carcinoma. 1st International conference of gonadotrophins & receptors (ICGR), April 13-17th, 2005, Athens, Georgia, USA.
Tozer AJ, Iles RK, Iammarrone E, Nica RA, Gillott CM, Xuesong WEN, Al-Shawaf T, Grudzinskas JG (2004). Characteristics of populations of granulosa cells from individual follicles in women undergoing 'coasting' during controlled ovarian stimulation (COS) for IVF. Hum Reprod 19(11):2561-8.
XS Wen, AJ Tozer, SA Butler, RK Iles. Biochemical evidence for follicular maturation (1): Changes of inhibins and activin A levels in follicular fluid from matched follicles; Biochemical evidence for follicular maturation (2): Production of progesterone, inhibins and activin by granulose cells from size-matched follicles. 23rd Joint Meeting of the British Endocrine Societies(BES), March 22-24, 2004, Brighton, UK.
XS Wen,SA Butler, RK Iles. Anti-hCG vaccine as a promising contraceptive method. Invited oral presentation for 3rd International Conference for the development of new technology , 22th-28st September 2003, Da Lian, China.
XS Wen, SA Butler, RK Iles. Changes of inhibin A, inhibin B, activin A levels in follicular fluid from individual follicles. International Workshop on Inhibin, Activin and Follistatin. , July 3-4th, 2003, Sienna, Italy.
I am fluent in Mandarin other than English.
1. Reproductive physiology
3. Cellular pathology
4. Immunohistochemical techniques
1. Assisted Reproductive technology
2. Cancer biology
3. hCG beta and epithelial cancers
Akhtar, Anam and Wang, Scarlet Xiaoyan and Ghali, Lucy and Bell, Celia M. and Wen, Xuesong (2016) Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers. Journal of Biomedical Research, 31 (2). pp. 1-12. ISSN 1674-8301 (Published online first)
Wen, Xuesong and Li, Dong and Farshori, Z and Wang, Xiaoyan and Ghali, Lucy (2015) The role of ectopic human chorionic gonadotropin beta subunit in inducing epithelial mesenchymal transition in human keratinocytes and its possible pathways. In: British Pharmacological Society Winder Conference 2014, 14-17 Dec 2014, Queen Elizabeth II Conference Centre London. (Published online first)
Niu, Qiaoli and Zhang, Qi and Xu, Weidong and Jiang, Yi and Xia, Ruidong and Bradley, Donal D. C. and Li, Dong and Wen, Xuesong (2015) Solution-processed anthracene-based molecular glasses as stable blue-light-emission laser gain media. Organic Electronics, 18 . pp. 95-100. ISSN 1566-1199
Wang, Xiaoyan and Li, Dong and Ghali, Lucy and Xia, Ruidong and Munoz, Leonardo P. and Garelick, Hemda and Bell, Celia M. and Wen, Xuesong (2016) Therapeutic potential of delivering arsenic trioxide into HPV-infected cervical cancer cells using liposomal nanotechnology. Nanoscale Research Letters, 11 (1). pp. 1-8. ISSN 1931-7573
Li, Dong and Wen, Xuesong and Ghali, Lucy and Al-Shalabi, F. M. and Docherty, S. M. and Purkis, P. and Iles, R. K. (2008) hCGβ expression by cervical squamous carcinoma - in vivohistological association with tumour invasion and apoptosis. Histopathology, 53 (2). pp. 147-155. ISSN 0309-0167