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      Dr Sandra Appiah

      ROLE: Associate Professor in Chemistry/Biochemistry
      SCHOOL: Science & Technology
      DEPARTMENT: Natural Sciences
      TELEPHONE: +44 (0)20 8411 5665
      EMAIL: S.Appiah@mdx.ac.uk
      1. Biography &
        Qualifications
      2. Learning &
        Teaching Interests
      3. Research Outputs &
        Interests
      4. Funded Research &
        Knowledge Exchange Projects
      5. Engagement &
        Impact

      • Biography &
        Qualifications

        Dr Sandra Appiah is an Associate Professor in Biochemistry and works at the Department of Natural Sciences, Middlesex University, UK.

        She has a Master of Science degree in Analytical Chemistry, a PhD in Biochemistry and a Master of Business degree in Senior Leadership. 

        In her role as a Faculty of Science and Technology Learning and Quality lead, she proactively works to maintain a high standard of student experience through initiatives on intentional inclusivity. She builds communities of enquiries to seek solutions for issues by collaborating with students, academics, Professional Services staff and businesses.


        Languages Spoken

      • Learning &
        Teaching Interests

        • Biochemistry
        • Chemistry
        • Pharmacognosy
        • Bioanalytical techniques
        • Molecular biology
        • Research methods

         

        CAREER HIGHLIGHTS

        • Experience gained as an academic in higher education (university sector) since 2008
        • Leadership roles in academia since 2010
          • Leads academic programmes and a wide range of academic modules
          • Held leading roles in university-wide research ethics
          • Leads sector-wide initiatives on inclusivity
          • Leads innovative research with translatable approaches to discover biomarkers for leukaemia and Alzheimer’s disease
          • Manage budgets and resources as a Research Lead
          • Excellent academic citizenship through serving on 10+ Boards, committees, networks, clusters, and Groups across the University

        KEY EXPERTISE– KNOWLEDGE & SKILLS

        • Academic teaching, learning, and assessment to enhance student outcomes
        • Leadership: team leadership, managing and diversity
        • Leading and developing people
        • Mentoring and supervision of colleagues and students
        • Organisational performance
        • Performance management and improving quality
        • Innovation and change
        • Research and data analysis
        • Research publications, funding and knowledge exchange
        • Stakeholder engagement and management
        • Building and sustaining collaborative partnerships

      • Research Outputs &
        Interests

         

        Sandra leads a productive Research Group studying aberrant cell signalling pathways involved in the pathogenesis of leukaemia and Alzheimer's disease with the goal of developing drug combinations designed to modulate different cell death processes. She also co-leads a Biosensor Research Group dedicated to developing novel biosensors for the early detection of chronic diseases.

        Publication Feed

        Intentionality for inclusivity - the journey at Middlesex University

        Roberts, Helen C. and Punev, Ivan Petkov and Allardyce, Duncan and Kyprianou, Anna and Appiah, Sandra S. and Megeney, Alison and Calin, Anastasia and Gallacher, Deeba and Mill, Rachel (2022) Intentionality for inclusivity - the journey at Middlesex University. Project Report. McGraw Hill. (Accepted/In press)

        Betulinic Acid–Doxorubicin-Drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model

        Vu, Milan and Kassouf, Nick and Appiah, Sandra S. (2021) Betulinic Acid–Doxorubicin-Drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model. Antioxidants , 10 (9). ISSN 2076-3921

        α-Mangostin and Doxorubicin Combination Synergistically Inhibited Cell Growth, Induced Cell Apoptosis with Increased Bak Protein and Decreased FLT3-ITD Phosphorylation in AML MOLM-13 Cell Line

        Osemeke, Cynthia and Wen, Xuesong and Garelick, Hemda and Appiah, Sandra S. (2021) α-Mangostin and Doxorubicin Combination Synergistically Inhibited Cell Growth, Induced Cell Apoptosis with Increased Bak Protein and Decreased FLT3-ITD Phosphorylation in AML MOLM-13 Cell Line. Clinical Oncology and Research , 4 (8). pp. 1-10. ISSN 2613-4942

        Doxorubicin selectively induced apoptosis through inhibition of a novel isoform of Bcl-2 in acute myeloid leukaemia MOLM-13 cells with reduced Beclin 1 expression

        Vu, Milan and Kassouf, Nick and Ofili, Rosemary Isioma and Lund, Torben and Bell, Celia M. and Appiah, Sandra S. (2020) Doxorubicin selectively induced apoptosis through inhibition of a novel isoform of Bcl-2 in acute myeloid leukaemia MOLM-13 cells with reduced Beclin 1 expression. International Journal of Oncology , 57 (1). pp. 113-121. ISSN 1019-6439

        Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 expression

        Vu, Milan and Kassouf, Nick and Ofili, Rosemary Isioma and Lund, Torben and Bell, Celia M. and Appiah, Sandra S. (2020) Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 expression. International Journal of Oncology , 57 (1). pp. 113-121. ISSN 1019-6439

        View more publications

      • Funded Research &
        Knowledge Exchange Projects

      • Engagement &
        Impact

        EXTERNAL ACTIVITIES & PROFESSIONAL MEMBERSHIP

        • Member - Chartered Manager - CMgr MCMI – since February 2023
        • External Examiner in Chemistry, London Metropolitan University, UK since November 2022
        • Member – McGraw-Hill Editorial Advisory Board since April 2022
        • Senior Fellow – Higher Education Academy (SFHEA) since 2021; Member since 2009
        • Fellow – Royal Society of Chemistry (FRSC) since 2019; Member since 2013
        • Member – The European Association for Cancer Research since 2019; EACR24681
        • Member – Royal Society of Biology (MRSB) since 2018; Membership Number P0130773

        ACTIVE MEMBERSHIPS OF COMMITTEES AND NETWORKS WITHIN Middlesex University

        §  Lead - Research Group (since 2016)

        §  Lead – Science and Technology (S&T) Learning and Teaching Showcase (since 2022)

        §  Deputy Chair - SAT Validation & Review Sub-Committee (since 2023)

        §  Member – Inclusive Curriculum Committee (since 2021)

        §  Member – S&T Teaching Fellows Community (since 2021)

        §  Member – S&T Learning and Teaching Research Group (since 2022)

        §  Member - Learning and Teaching Enhancement Committee (Since 2023)

        §  Member - Prevent Implementation Working Group (since 2022)

        §  Member - Natural Science Departmental Science Advisory Committee (since 2022)

        §  Member – Departmental Research and Knowledge Exchange Committee (since 2022)

        §  Member - CAPE Learning Framework Review Committee (since 2023)

        §  Project Lead – Successes in Academia Initiative (MU and sector-wide) (since 2020)

        §  Co-chair – MDX-ARN (Anti-Racism Network) (since 2022)

        §  Member – Equality, Diversity and Inclusivity Committee (EDIC) (since 2022)

        §  Whistleblowing Designated Assessor (Since 2022)

        §  Budget holder for the Ellis Snitcher Award for Integrative Medicine (since 2022)

         

         

        NOTABLE PREVIOUS LEAD ROLES

        Deputy Chair – University Research Ethics Committee (2019 - 2022)

        Chair – Natural Science Research Ethics Subcommittee (2019 – 2023)

        Lead for Ethics on the Current Research Information System (CRIS) ITT Project Board (in 2022)

        Lead – Race Equality Charter Staff Self-Assessment Team (2021-2022)

        Programme Chair – MDX Research Student Summer Research Conference (2021)

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