Dr Sandra Appiah is an Associate Professor in Biochemistry and works at the Department of Natural Sciences, Middlesex University, UK.
She has a Master of Science degree in Analytical Chemistry, a PhD in Biochemistry and a Master of Business degree in Senior Leadership.
In her role as a Faculty of Science and Technology Learning and Quality lead, she proactively works to maintain a high standard of student experience through initiatives on intentional inclusivity. She builds communities of enquiries to seek solutions for issues by collaborating with students, academics, Professional Services staff and businesses.
KEY EXPERTISE– KNOWLEDGE & SKILLS
Sandra leads a productive Research Group studying aberrant cell signalling pathways involved in the pathogenesis of leukaemia and Alzheimer's disease with the goal of developing drug combinations designed to modulate different cell death processes. She also co-leads a Biosensor Research Group dedicated to developing novel biosensors for the early detection of chronic diseases.
Roberts, Helen C. and Punev, Ivan Petkov and Allardyce, Duncan and Kyprianou, Anna and Appiah, Sandra S. and Megeney, Alison and Calin, Anastasia and Gallacher, Deeba and Mill, Rachel (2022) Intentionality for inclusivity - the journey at Middlesex University. Project Report. McGraw Hill. (Accepted/In press)
Vu, Milan and Kassouf, Nick and Appiah, Sandra S. (2021) Betulinic Acid–Doxorubicin-Drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model. Antioxidants , 10 (9). ISSN 2076-3921
Osemeke, Cynthia and Wen, Xuesong and Garelick, Hemda and Appiah, Sandra S. (2021) α-Mangostin and Doxorubicin Combination Synergistically Inhibited Cell Growth, Induced Cell Apoptosis with Increased Bak Protein and Decreased FLT3-ITD Phosphorylation in AML MOLM-13 Cell Line. Clinical Oncology and Research , 4 (8). pp. 1-10. ISSN 2613-4942
Vu, Milan and Kassouf, Nick and Ofili, Rosemary Isioma and Lund, Torben and Bell, Celia M. and Appiah, Sandra S. (2020) Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 expression. International Journal of Oncology , 57 (1). pp. 113-121. ISSN 1019-6439
Vu, Milan and Kassouf, Nick and Bell, Celia M. and Appiah, Sandra S. (2018) Betulinic acid-doxorubicin drug combination synergistically supresses cell viability and enhances apoptotic death in acute myeloid leukaemia cell lines by increasing Bax/Bcl-2 ratio. In: NCRI Cancer Conference (2018), 04-06 Nov 2018, Glasgow, Scotland.
EXTERNAL ACTIVITIES & PROFESSIONAL MEMBERSHIP
ACTIVE MEMBERSHIPS OF COMMITTEES AND NETWORKS WITHIN Middlesex University
§ Lead - Research Group (since 2016)
§ Lead – Science and Technology (S&T) Learning and Teaching Showcase (since 2022)
§ Deputy Chair - SAT Validation & Review Sub-Committee (since 2023)
§ Member – Inclusive Curriculum Committee (since 2021)
§ Member – S&T Teaching Fellows Community (since 2021)
§ Member – S&T Learning and Teaching Research Group (since 2022)
§ Member - Learning and Teaching Enhancement Committee (Since 2023)
§ Member - Prevent Implementation Working Group (since 2022)
§ Member - Natural Science Departmental Science Advisory Committee (since 2022)
§ Member – Departmental Research and Knowledge Exchange Committee (since 2022)
§ Member - CAPE Learning Framework Review Committee (since 2023)
§ Project Lead – Successes in Academia Initiative (MU and sector-wide) (since 2020)
§ Co-chair – MDX-ARN (Anti-Racism Network) (since 2022)
§ Member – Equality, Diversity and Inclusivity Committee (EDIC) (since 2022)
§ Whistleblowing Designated Assessor (Since 2022)
§ Budget holder for the Ellis Snitcher Award for Integrative Medicine (since 2022)
NOTABLE PREVIOUS LEAD ROLES
Deputy Chair – University Research Ethics Committee (2019 - 2022)
Chair – Natural Science Research Ethics Subcommittee (2019 – 2023)
Lead for Ethics on the Current Research Information System (CRIS) ITT Project Board (in 2022)
Lead – Race Equality Charter Staff Self-Assessment Team (2021-2022)
Programme Chair – MDX Research Student Summer Research Conference (2021)