Brain cancer diagnosis and therapy
Look for blood biomarkers using the NALIA system (see Project 4) to see whether they can provide early diagnosis of brain cancer, particularly glioblastoma, and also monitoring of therapy.
We will construct iron nanoparticles to target the brain tumour cells because they should permit the application of the highly economical Electrical Impedance Imaging Technology and permit thermal ablation of the tumour by application of an external energy source to targeted nanoparticles injected directly into the tumour mass.
Goals
1) Diagnostic microarray for early diagnosis and monitoring of brain tumours.
2) Economical imaging of these tumours.
3) Thermal ablation of tumours ("I'd rather have a needle than a knife").
Project team
Dr. A. Tizzard Leader
Prof. R. Bayford
Scientific support
Dr. S. Butler
Scientific support
Research Assistant
Biological testing of nanoparticles
Midatech Ltd.
Nanoparticle synthesis
Prof. A. Dalgleish, St.
Testing tumour inhibition
George's Hosp. M.Sch. Surgeon, Kings Coll. Hosp.
Provide clinical material