The mission of this group is to investigate cellular mechanisms of disease in order to establish novel biomarkers for disease diagnosis and monitoring. We use a variety of technologies to do this including antibody-based detection, in-vitro models, impedance-based biosensors and mass spectrometry-based detection systems. A key and emerging area is to use biomarker information in order to discover and test novel therapeutic targets for treatment. The group encompasses a range of expertise in cellular and molecular pathology, cancer, reproductive science, microbiology and pharmaceutical and analytical chemistry.
Key targets currently include breast, ovarian, cervical and colorectal cancers, pregnancy disorders (pre-eclampsia), dementia, wound healing and diabetes. The group collaborates with other research groups in Biomedical Sciences and other Departments within Middlesex University. We also have ongoing collaborations with UCL, Imperial College and Charité Universitätsmedizin Berlin.